Carlsmed, Inc.

Clear Guide Medical, Inc. is a privately held medical device company headquartered in Baltimore, Maryland, that develops image-guided technologies utilizing artificial intelligence and augmented reality.

Berman Medical is a medical technology company developing an aesthetics and dermatology platform focused on facial injections. Their system combines advanced imaging, spatial tracking, and artificial intelligence to provide clinicians with real-time, patient-specific anatomical navigation during treatments.

Alphatec Holdings, Inc. is a medical technology firm dedicated to engineering and advancing solutions for the surgical management of spinal conditions. Its product array includes the Alpha InformatiX platform, notably the SafeOp Neural InformatiX System, which is engineered to reduce the likelihood of nerve injury during surgery. For access and positioning, Alphatec offers systems such as the Sigma transforaminal lumbar interbody fusion pedicle-based access system, the Sigma PTP Access and Patient Positioning System, and the Squadron lateral retractor, all designed to optimize surgical outcomes. The company's robust line of spinal fixation devices features the Invictus Spinal Fixation System, capable of addressing various thoracolumbar pathologies, alongside its minimally invasive SingleStep System and adaptable Modular Fixation Systems, which enhance screw modularity. Further fixation options include the OsseoScrew system for spinal column restoration and the comprehensive Arsenal spinal fixation platform, catering to a spectrum of degenerative to deformity procedures. Alphatec also provides anterior lumbar plating solutions like the Aspida Anterior Lumbar Plating System for interbody fusion and the AMP Anti-Migration Plate, in addition to cervical fixation options such as the OCT Spinal Fixation System, the Trestle Luxe Anterior Cervical Plate System, and the Insignia Anterior Cervical Plate System. Its portfolio extends to interbody implants, including IdentiTi Porous Ti, Transcend Lateral, and Battalion Posterior Implants. A comprehensive suite of biologics is also available, featuring Cervical Structural Allograft Spacers, 3D ProFuse Demineralized Bone Scaffold, Neocore Osteoconductive Matrix, Alphagraft Demineralized and Cellular Bone Matrix, and Amnioshield Amniotic Tissue Barrier. The company additionally offers EOS imaging products. Alphatec Holdings markets its diverse product range throughout the United States via a network of independent distributors and its own direct sales force. Established in 1990, the company's headquarters are located in Carlsbad, California.

Cutting Edge Spine, llcMedical DevicesUnited States

71% matchPrivate

Cutting Edge Spine designs, develops, and commercializes orthopedic and spinal implant systems, including SI fixation and interbody systems. The company serves orthopedic surgeons and neurosurgeons by providing bio-active, trabecular fixation technologies aimed at improving clinical outcomes.

OnPoint Knee, Inc.Medical DevicesUnited States

70% matchPrivate

OnPoint Knee, Inc. develops OnPoint AR, an advanced augmented reality and AI-powered system designed for spine surgeons. The technology projects virtual surgical guides, implants, and 3D anatomical landmarks directly onto the patient to improve precision, maintain tactile feedback, and streamline workflows during spine surgery.

NovApproach Spine, LLCMedical DevicesUnited States

70% matchPrivate

NovApproach Spine, LLC designs and develops medical devices and surgical approaches for spine and spinal access surgeons. The company's flagship product, the OneLIF device, is an interbody implant system created to simplify anterior lumbar spine surgery, improve procedural efficiency, and accommodate a wide range of patient anatomies.