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Kubota Pharmaceutical Holdings Co., Ltd., an international entity established in Tokyo, Japan, in 2002, focuses on the creation and advancement of a diverse range of pharmaceutical treatments and medical devices. A primary asset in their development pipeline is emixustat hydrochloride, a drug currently undergoing Phase III clinical trials for Stargardt disease and Phase II trials for proliferative diabetic retinopathy. Beyond its pharmaceutical endeavors, the company is also innovating in medical technology, specifically with a patient-centric ophthalmology suite designed for remote retinal monitoring. This advanced suite features both miniature, home-use optical coherence tomography (OCT) devices and high-resolution OCT technology adapted from NASA. Furthermore, Kubota Pharmaceutical Holdings is developing a wearable device aimed at controlling myopia.

Headquartered in Tokyo, Japan, Seikagaku Corporation, established in 1947, specializes in the global development, manufacturing, and distribution of pharmaceuticals and medical devices, with a core focus on glycoconjugates. The company, which was formerly known as K.K. Seikagaku Kenkyusho until its name change in 1962, operates through two primary segments: Pharmaceuticals and LAL. Its product portfolio encompasses a range of therapeutic and surgical solutions. For joint health, Seikagaku provides intra-articular injections like ARTZ, ARTZ Dispo, VISCO-3, and SUPARTZ FX, designed to enhance joint function. The company also supplies ophthalmic surgical aids such as OPEGAN, OPEGAN Hi, and SHELLGAN, alongside MucoUp for endoscopic mucosal resection. Other notable offerings include Gel-One, a cross-linked hyaluronate hydrogel addressing knee osteoarthritis, and HERNICORE for lumbar disc herniation. Beyond finished products, Seikagaku is a supplier of bulk materials, specifically sodium hyaluronate and sodium chondroitin sulfate, which find application in various pharmaceutical and cosmetic formulations. Furthermore, the company develops and markets specialized endotoxin-detecting reagents, including Pyrochrome, ENDOSPECY, and TOXICOLOR, which are crucial for quality assurance in injectable pharmaceuticals, biological products, medical devices, manufacturing operations, and dialysate water quality. Its offerings also extend to oral care, featuring the KINUSUI Spray mouthwash. Seikagaku maintains a robust development pipeline, with promising candidates such as SI-6603 for lumbar disc herniation, SI-614 (a modified hyaluronate for dry eyes), SI-613 for osteoarthritis, SI-613-ETP targeting enthesopathy, and SI-449, a powdered adhesion barrier.

Bausch Health Companies Inc.BHC · PharmaceuticalsLaval, Canada

66% matchPublic

Bausch Health Companies Inc., together with its associated entities, is engaged in the development, manufacturing, and commercialization of a diverse portfolio of pharmaceutical products, medical devices, and over-the-counter remedies. Its primary therapeutic focus areas include ophthalmology, digestive health, and dermatology. The enterprise conducts its operations through five principal divisions: Bausch + Lomb, Salix, International Rx, Ortho Dermatologics, and Diversified Products. The Bausch + Lomb segment is dedicated to vision care, encompassing surgical instruments, consumer eye health products, and ophthalmic pharmaceuticals. Salix specializes in delivering gastroenterology-specific products exclusively within the United States. The International Rx division markets Solta products, a range of branded and generic pharmaceuticals, OTC items, medical devices, and Bausch + Lomb offerings across diverse geographies including Canada, Europe, Asia, Australia, Latin America, Africa, and the Middle East. Ortho Dermatologics focuses on dermatological products in the U.S., in addition to distributing Solta's medical aesthetic devices globally. Finally, the Diversified Products segment supplies pharmaceutical solutions for neurology and other therapeutic categories, as well as generic medications and dental products, all within the U.S. The company was formerly known as Valeant Pharmaceuticals International, Inc., officially changing its name to Bausch Health Companies Inc. in July 2018. Its corporate headquarters are located in Laval, Canada.

EyePoint Pharmaceuticals, Inc. is a pharmaceutical firm dedicated to the creation and marketing of ophthalmic solutions for various eye ailments. Its operations span the United States, China, and the United Kingdom. Among its commercialized product portfolio are ILUVIEN, an injectable, sustained-release micro-insert designed to treat diabetic macular edema, and YUTIQ, an intravitreal implant containing fluocinolone acetonide, which targets chronic non-infectious uveitis impacting the posterior segment of the eye. The company also offers DEXYCU, a dexamethasone intraocular suspension, utilized to manage post-operative ocular inflammation, such as that occurring after cataract surgery. Looking ahead, EyePoint is actively developing several pipeline therapies. This includes EYP-1901, a novel, bioerodible tyrosine kinase inhibitor currently formulated for twice-yearly administration, which is under development for conditions like wet age-related macular degeneration, diabetic retinopathy, and retinal vein occlusion. Additionally, YUTIQ50 is being advanced as a treatment for chronic non-infectious uveitis affecting the posterior region of the eye. To bolster its market reach and development efforts, the company maintains strategic alliances with entities such as Alimera Sciences, Inc., Bausch & Lomb, OncoSil Medical UK Limited, Ocumension Therapeutics, and Equinox Science, LLC. Furthermore, a commercial collaboration with ImprimisRx PA, Inc. specifically focuses on the joint promotion of DEXYCU for inflammation following ocular surgery. Incorporated in 1987, the organization was previously known as pSivida Corp. before officially rebranding as EyePoint Pharmaceuticals, Inc. in March 2018. Its corporate headquarters are situated in Watertown, Massachusetts.

Morishita Jintan Co., Ltd. is a Japanese enterprise that manufactures and distributes a diverse array of products, encompassing pharmaceuticals, quasi-pharmaceuticals, medical devices, and food items. The company's operations are divided into two main segments: Healthcare Business and Capsule Business. The Healthcare Business division is responsible for the production and sale of its proprietary Jintan branded goods, and also provides original equipment manufacturing (OEM) services for dietary supplements, cosmetic products, and various food items. Concurrently, the Capsule Business division handles both original equipment and design manufacturing (OEM/ODM) for pharmaceutical and food sectors, in addition to innovating and developing capsules for industrial applications. Established in 1893, the company's headquarters are located in Osaka, Japan.

大塚ホールディングス4578 · PharmaceuticalsTokyo, Japan

64% matchPublic

Otsuka Holdings Co., Ltd. engages in the pharmaceuticals, nutraceuticals, consumer products, and other businesses worldwide. It develops pharmaceutical products in the fields of psychiatry, neurology, oncology, cardiovascular and renal system, autoimmune space digestive system, ophthalmology, and diagnostics, as well as intravenous solutions and medical devices. It also provides clinical testing, medical equipment and tools, food products, cosmetics, functional food products, chemical products, soft drinks, beverages, analytical and measurement equipment, nutritional products, vehicle headlight testers, synthetic resin molded products, paper products, quasi-drugs, household products, and packaging materials and electronic parts. In addition, it offers IT solutions; adhesive tapes; flaky titanate and compounds; infusion and clinical nutrition products; hydrazine; plant-based food products; reinsurance underwriting services; wine; stable isotopes; food supplements; software and services for management of mental healthcare systems; anticancer drugs; terracess; bio-pesticides; dietetic food products; spring and mineral water; and polyolefin foams. Further, it engages in the warehousing and transport, medical device operational management, shared service, environmental health management, and venture capital and incubation businesses; rental of medical devices and related products; purchase and sale of agricultural products; import and export trading business; tuberculosis research and development activities; rental of space and office businesses; manufacturing and development of xenotransplantation products; and processing and marketing of functional films, as well as planning, design, production, and construction of ceramic boards and arts, ceramic walls, reliefs, terracotta, ceramic OT and portraits, and ceramic sign boards; and operation of travel agency, and Hotel Ridge and California Table. The company was founded in 1921 and is headquartered in Chiyoda, Japan.