MSICS Pharma

Pharma Two BPharmaceuticalsIsrael

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Pharma Two B Ltd. is a late-clinical stage biopharmaceutical company headquartered in Kiryat Ono, Israel. The company focuses on developing pharmaceutical treatments and therapeutic products for neurological and related medical conditions. It has pursued corporate growth initiatives, including planned public market transactions via mergers.

Abital Pharma Pipelines is an incubator in Israel dedicated to advancing life science innovation. The company collaborates with the Naiot incubator to develop drugs targeting the central nervous system.

Mindset Pharma Inc.PharmaceuticalsCanada

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Mindset Pharma Inc. is a drug discovery and development company based in Toronto, Canada, focused on creating optimized, patentable next-generation psychedelic medicines.

Mapi Pharma is an Israeli pharmaceutical company that develops complex generic and proprietary drug products, with a focus on long-acting injectable formulations. Its products are intended for patients and healthcare providers, and the company works with pharmaceutical partners to develop and commercialize treatments, including therapies for neurological conditions such as multiple sclerosis.

ENTROPY NEURODYNAMICS LIMITEDENP · Pharmaceuticals, Biotechnology & Life SciencesCamberwell, Australia

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Entropy Neurodynamics Limited operates as a clinical-stage pharmaceutical company, dedicated to pioneering novel formulations for psilocin administration. These formulations are intended for use alongside psychotherapy, aiming to tackle medical conditions with pressing unmet needs across Australia, Canada, Switzerland, and the United States. The firm's flagship development is TRP-8803, an intravenously infused psilocin formulation that has successfully concluded Phase 2 clinical trials. These trials investigated its potential to treat binge eating disorder, fibromyalgia, irritable bowel syndrome, abdominal pain, and visceral tenderness. Additionally, the company is advancing TRP-8802, a synthetic, orally administered psilocybin compound. TRP-8802 is currently undergoing Phase 2a clinical trials for binge eating and is in Phase 2 clinical development for fibromyalgia and irritable bowel syndrome. Established in 2019 and headquartered in Camberwell, Australia, the company adopted its current name, Entropy Neurodynamics Limited, in November 2025, having previously operated as Tryptamine Therapeutics Limited.

SciSparc Ltd. is a pharmaceutical company in the clinical development phase, specializing in creating medications derived from cannabinoid molecules. Their therapeutic pipeline encompasses several key drug candidates: SCI-110, which is being investigated for the treatment of Tourette syndrome, obstructive sleep apnea, and agitation associated with Alzheimer's disease; SCI-160, designed to address pain; and SCI-210, targeting autism spectrum disorder and epilepsy. The company has formed strategic alliances to further its goals. A partnership with Procaps focuses on the development and eventual commercial manufacturing of SCI-110, as well as CannAmide, an oral palmitoylethanolamide in a soft gel capsule. SciSparc is also collaborating with the Sheba Fund for Health Services and Research to explore SCI-210's potential in managing status epilepticus. Additionally, it has teamed up with The Israeli Medical Center for Alzheimer's to conduct a Phase IIa clinical trial, evaluating the safety, tolerability, and effectiveness of SCI-110 for patients experiencing Alzheimer's disease and agitation. Founded in 2004, the company initially operated under the name Therapix Biosciences Ltd. before changing to SciSparc Ltd. in January 2021. Its main corporate office is located in Tel Aviv-Yafo, Israel.